Biofilm is a serious challenge to wound healing1,2

All wounds contain bioburden and are at risk for developing biofilm2-4

  • Biofilm is present in most chronic wounds3
  • Unmanaged bioburden in any wound type can progress to biofilm2,4

biofilm_dispersion_chart_11Adapted from Phillips et al, 2010.

Biofilm is often impossible to see and difficult to treat5,6

  • Biofilm is underdiagnosed because it is often invisible to the eye and standard laboratory tests cannot detect it6
  • Sharp debridement does not completely eliminate biofilm, and biofilm is not typically susceptible to antibiotics7

Biofilm impairs wound healing and can lead to infection2,7,8

  • Biofilm causes prolonged inflammation, which prevents healing2
  • Approximately 80% of all human infections are linked to biofilm7

References: 1. Attinger C, Wolcott R. Adv Wound Care (New Rochelle). 2012;1(3):127-132. 2. Wolcott R, Cutting KF, Ruiz JC. Association for the Advancement of Wound Care. Publication No. UKCT-A0021. 2008:12-17. 3. Percival SL, Vuotto C, Donelli G, Lipsky BA. Adv Wound Care. 2015;4(7):389-397. 4. Mulder GD, Cavorsi JP, Lee DK. Wounds. 2007;19(7):173-182. 5. Phillips PL, Wolcott RD, Fletcher J, Schultz GS. Biofilms made easy. Wounds International website. www.woundsinternational.com/made-easys/view/biofilms-made-easy. Published May 17, 2010. Accessed December 20, 2016. 6. Black CE, Costerton JW. Surg Clin North Am. 2010;90(6):1147-1160. 7. Wolcott R, Dowd S. Plast Reconstr Surg. 2011;127(suppl 1):28S-35S. 8. Schierle CF, De la Garza M, Mustoe TA, Galiano RD. Wound Repair Regen. 2009;17(3):354-359.